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Mouse model of colorectal cancer: orthotopic co-implantation of tumor and stroma cells in cecum and rectum

In vivo interrogation of the functional role of genes implicated in colorectal cancer (CRC) is limited by the need for physiological models that mimic the disease. Here, we describe a protocol that provides the steps required for the orthotopic co-implantation of tumoral and stromal cells into the c...

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Библиографические подробности
Опубликовано в: :STAR Protoc
Главные авторы: Kasashima, Hiroaki, Duran, Angeles, Cid-Diaz, Tania, Muta, Yu, Kinoshita, Hiroto, Batlle, Eduard, Diaz-Meco, Maria T., Moscat, Jorge
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843928/
https://ncbi.nlm.nih.gov/pubmed/33554135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100297
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