Mouse model of colorectal cancer: orthotopic co-implantation of tumor and stroma cells in cecum and rectum

In vivo interrogation of the functional role of genes implicated in colorectal cancer (CRC) is limited by the need for physiological models that mimic the disease. Here, we describe a protocol that provides the steps required for the orthotopic co-implantation of tumoral and stromal cells into the c...

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Detalhes bibliográficos
Publicado no:STAR Protoc
Main Authors: Kasashima, Hiroaki, Duran, Angeles, Cid-Diaz, Tania, Muta, Yu, Kinoshita, Hiroto, Batlle, Eduard, Diaz-Meco, Maria T., Moscat, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843928/
https://ncbi.nlm.nih.gov/pubmed/33554135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100297
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