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Mouse model of colorectal cancer: orthotopic co-implantation of tumor and stroma cells in cecum and rectum

In vivo interrogation of the functional role of genes implicated in colorectal cancer (CRC) is limited by the need for physiological models that mimic the disease. Here, we describe a protocol that provides the steps required for the orthotopic co-implantation of tumoral and stromal cells into the c...

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Enregistré dans:
Détails bibliographiques
Publié dans:STAR Protoc
Auteurs principaux: Kasashima, Hiroaki, Duran, Angeles, Cid-Diaz, Tania, Muta, Yu, Kinoshita, Hiroto, Batlle, Eduard, Diaz-Meco, Maria T., Moscat, Jorge
Format: Artigo
Langue:Inglês
Publié: Elsevier 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843928/
https://ncbi.nlm.nih.gov/pubmed/33554135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100297
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