Prediction of nasal spray drug absorption influenced by mucociliary clearance

Evaluation of nasal spray drug absorption has been challenging because deposited particles are consistently transported away by mucociliary clearance during diffusing through the mucus layer. This study developed a novel approach combining Computational Fluid Dynamics (CFD) techniques with a 1-D muc...

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Udgivet i:PLoS One
Main Authors: Shang, Yidan, Inthavong, Kiao, Qiu, Dasheng, Singh, Narinder, He, Fajiang, Tu, Jiyuan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7842989/
https://ncbi.nlm.nih.gov/pubmed/33507973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246007
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