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Prediction of nasal spray drug absorption influenced by mucociliary clearance

Evaluation of nasal spray drug absorption has been challenging because deposited particles are consistently transported away by mucociliary clearance during diffusing through the mucus layer. This study developed a novel approach combining Computational Fluid Dynamics (CFD) techniques with a 1-D muc...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Shang, Yidan, Inthavong, Kiao, Qiu, Dasheng, Singh, Narinder, He, Fajiang, Tu, Jiyuan
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7842989/
https://ncbi.nlm.nih.gov/pubmed/33507973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246007
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