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Prediction of nasal spray drug absorption influenced by mucociliary clearance

Evaluation of nasal spray drug absorption has been challenging because deposited particles are consistently transported away by mucociliary clearance during diffusing through the mucus layer. This study developed a novel approach combining Computational Fluid Dynamics (CFD) techniques with a 1-D muc...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shang, Yidan, Inthavong, Kiao, Qiu, Dasheng, Singh, Narinder, He, Fajiang, Tu, Jiyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7842989/
https://ncbi.nlm.nih.gov/pubmed/33507973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246007
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