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Prediction of nasal spray drug absorption influenced by mucociliary clearance

Evaluation of nasal spray drug absorption has been challenging because deposited particles are consistently transported away by mucociliary clearance during diffusing through the mucus layer. This study developed a novel approach combining Computational Fluid Dynamics (CFD) techniques with a 1-D muc...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Shang, Yidan, Inthavong, Kiao, Qiu, Dasheng, Singh, Narinder, He, Fajiang, Tu, Jiyuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7842989/
https://ncbi.nlm.nih.gov/pubmed/33507973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246007
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