Rebamipide ameliorates indomethacin-induced small intestinal damage and proton pump inhibitor-induced exacerbation of this damage by modulation of small intestinal microbiota

Non-steroidal anti-inflammatory drugs (NSAIDs) induce small intestinal damage. It has been reported that rebamipide, a mucoprotective drug, exerts a protective effect against NSAID-induced small intestinal damage; however, the underlying mechanism remains unknown. In this study, we investigated the...

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Pubblicato in:PLoS One
Autori principali: Tanigawa, Tetsuya, Watanabe, Toshio, Higashimori, Akira, Shimada, Sunao, Kitamura, Hiroyuki, Kuzumoto, Takuya, Nadatani, Yuji, Otani, Koji, Fukunaga, Shusei, Hosomi, Shuhei, Tanaka, Fumio, Kamata, Noriko, Nagami, Yasuaki, Taira, Koichi, Shiba, Masatsugu, Suda, Wataru, Hattori, Masahira, Fujiwara, Yasuhiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7842908/
https://ncbi.nlm.nih.gov/pubmed/33507971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0245995
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