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Dual sgRNA-based Targeted Deletion of Large Genomic Regions and Isolation of Heritable Cas9-free Mutants in Arabidopsis

CRISPR/Cas9 system directed by a gene-specific single guide RNA (sgRNA) is an effective tool for genome editing such as deletions of few bases in coding genes. However, targeted deletion of larger regions generate loss-of-function alleles that offer a straightforward starting point for functional di...

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Detalhes bibliográficos
Publicado no:Bio Protoc
Main Authors: Jin, Yu, Marquardt, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Bio-Protocol 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7842341/
https://ncbi.nlm.nih.gov/pubmed/33659450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3796
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