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Loss of H3K27 methylation identifies poor outcomes in adult-onset acute leukemia

BACKGROUND: Acute leukemia is an epigenetically heterogeneous disease. The intensity of treatment is currently guided by cytogenetic and molecular genetic risk classifications; however these incompletely predict outcomes, requiring additional information for more accurate outcome predictions. We aim...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clin Epigenetics
Hauptverfasser: van Dijk, A. D., Hoff, F. W., Qiu, Y. H., Chandra, J., Jabbour, E., de Bont, E. S. J. M., Horton, T. M., Kornblau, S. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7841917/
https://ncbi.nlm.nih.gov/pubmed/33509276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01011-x
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