Loss of H3K27 methylation identifies poor outcomes in adult-onset acute leukemia

BACKGROUND: Acute leukemia is an epigenetically heterogeneous disease. The intensity of treatment is currently guided by cytogenetic and molecular genetic risk classifications; however these incompletely predict outcomes, requiring additional information for more accurate outcome predictions. We aim...

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Udgivet i:Clin Epigenetics
Main Authors: van Dijk, A. D., Hoff, F. W., Qiu, Y. H., Chandra, J., Jabbour, E., de Bont, E. S. J. M., Horton, T. M., Kornblau, S. M.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7841917/
https://ncbi.nlm.nih.gov/pubmed/33509276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01011-x
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