Notch signaling drives synovial fibroblast identity and arthritis pathology

The synovium is a mesenchymal tissue composed mainly of fibroblasts with a lining and sublining that surrounds the joints. In rheumatoid arthritis (RA), the synovial tissue undergoes marked hyperplasia, becomes inflamed and invasive and destroys the joint(1,2). Recently, we and others found that a s...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nature
Main Authors: Wei, Kevin, Korsunsky, Ilya, Marshall, Jennifer L., Gao, Anqi, Watts, Gerald F. M., Major, Triin, Croft, Adam P., Watts, Jordan, Blazar, Philip, Lange, Jeffrey, Thornhill, Thomas, Filer, Andrew, Raza, Karim, Donlin, Laura T., Siebel, Christian W., Buckley, Christopher D., Raychaudhuri, Soumya, Brenner, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7841716/
https://ncbi.nlm.nih.gov/pubmed/32499639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2222-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados