Synovial DKK1 expression is regulated by local glucocorticoid metabolism in inflammatory arthritis

INTRODUCTION: Inflammatory arthritis is associated with increased bone resorption and suppressed bone formation. The Wnt antagonist dickkopf-1 (DKK1) is secreted by synovial fibroblasts in response to inflammation and this protein has been proposed to be a master regulator of bone remodelling in inf...

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Библиографические подробности
Главные авторы: Hardy, Rowan, Juarez, Maria, Naylor, Amy, Tu, Jinwen, Rabbitt, Elizabeth H, Filer, Andrew, Stewart, Paul M, Buckley, Christopher D, Raza, Karim, Cooper, Mark S
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580537/
https://ncbi.nlm.nih.gov/pubmed/23079210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4065
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