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Synovial DKK1 expression is regulated by local glucocorticoid metabolism in inflammatory arthritis
INTRODUCTION: Inflammatory arthritis is associated with increased bone resorption and suppressed bone formation. The Wnt antagonist dickkopf-1 (DKK1) is secreted by synovial fibroblasts in response to inflammation and this protein has been proposed to be a master regulator of bone remodelling in inf...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3580537/ https://ncbi.nlm.nih.gov/pubmed/23079210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4065 |
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