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Local and systemic glucocorticoid metabolism in inflammatory arthritis
BACKGROUND: Isolated, primary synovial fibroblasts generate active glucocorticoids through expression of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). This enzyme produces cortisol from inactive cortisone (and prednisolone from prednisone). OBJECTIVE: To determine how intact synovial tissue me...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMJ Publishing Group
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2564803/ https://ncbi.nlm.nih.gov/pubmed/18420938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2008.090662 |
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