DKK1 expression by synovial fibroblasts in very early rheumatoid arthritis associates with lymphocyte adhesion in an in vitro flow co-culture system

BACKGROUND: Synovial fibroblasts play a key role in joint destruction and regulation of the inflammatory infiltrate in established rheumatoid arthritis (RA). The mechanisms by which this occurs in the earliest stages of RA are largely unknown. We investigated the role of Dickkopf-related protein 1 (...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Juarez, Maria, McGettrick, Helen M., Scheel-Toellner, Dagmar, Yeo, Lorraine, Spengler, Julia, de Paz, Banesa, Hardy, Rowan, Cooper, Mark, Raza, Karim, Buckley, Christopher D., Filer, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718043/
https://ncbi.nlm.nih.gov/pubmed/26782930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-0915-3
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