Time-Dependent Distribution of Hydroxychloroquine in Cynomolgus Macaques Using Population Pharmacokinetic Modeling Method

To evaluate the biodistribution of hydroxychloroquine (HCQ) in cynomolgus macaques and receive dynamic quantitative relationship between plasma, blood, and lung tissue concentration using the population pharmacokinetic modeling method, seventeen cynomolgus macaques were divided into six groups accor...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Pharmacol
Egile Nagusiak: Liu, Qi, Bi, Guofang, Chen, Guiying, Guo, Xuan, Tu, Siqi, Tong, Xiaolin, Xu, Man, Liu, Mengjie, Wang, Bei, Jiang, Hongliang, Wang, Jufeng, Li, Haiyan, Wang, Kun, Liu, Dongyang, Song, Chunli
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2021
Gaiak:
Pharmacology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7841297/
https://ncbi.nlm.nih.gov/pubmed/33519466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.602880
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