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Isolation and characterization of arylacetamide deacetylase in cynomolgus macaques
Arylacetamide deacetylase (AADAC), a microsomal serine esterase, hydrolyzes drugs, such as flutamide, phenacetin and rifampicin. Because AADAC has not been fully investigated at molecular levels in cynomolgus macaques, the non-human primate species widely used in drug metabolism studies, cynomolgus...
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Publicado no: | J Vet Med Sci |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Japanese Society of Veterinary Science
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4488411/ https://ncbi.nlm.nih.gov/pubmed/25715734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.14-0496 |
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