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Nuclear translocation of the receptor tyrosine kinase c-MET reduces the treatment efficacies of olaparib and gemcitabine in pancreatic ductal adenocarcinoma cells

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer that lack effective therapeutic strategies. The response rate of PDAC for treatment with gemcitabine, a current first-line chemotherapeutic for this tumor, is lower than 20%. Identifying key targetable molecules that mediate gemcitabine...

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Bibliografiske detaljer
Udgivet i:Am J Cancer Res
Main Authors: Gao, Yuan, Chen, Mei-Kuang, Chu, Yu-Yi, Yang, Liuqing, Yu, Dihua, Liu, Yingbin, Hung, Mien-Chie
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840709/
https://ncbi.nlm.nih.gov/pubmed/33520371
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