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Multistep Changes in Amyloid Structure Induced by Cross-Seeding on a Rugged Energy Landscape

Amyloid fibrils are aberrant protein aggregates associated with various amyloidoses and neurodegenerative diseases. It is recently indicated that structural diversity of amyloid fibrils often results in different pathological phenotypes, including cytotoxicity and infectivity. The diverse structures...

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Bibliografski detalji
Izdano u:Biophys J
Glavni autori: Yuzu, Keisuke, Yamamoto, Naoki, Noji, Masahiro, So, Masatomo, Goto, Yuji, Iwasaki, Tetsushi, Tsubaki, Motonari, Chatani, Eri
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840402/
https://ncbi.nlm.nih.gov/pubmed/33340544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.12.005
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