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Modeling of Hidden Structures Using Sparse Chemical Shift Data from NMR Relaxation Dispersion

NMR relaxation dispersion measurements report on conformational changes occurring on the μs-ms timescale. Chemical shift information derived from relaxation dispersion can be used to generate structural models of weakly populated alternative conformational states. Current methods to obtain such mode...

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Détails bibliographiques
Publié dans:Biophys J
Auteurs principaux: Fenwick, R. Bryn, Oyen, David, van den Bedem, Henry, Dyson, H. Jane, Wright, Peter E.
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840400/
https://ncbi.nlm.nih.gov/pubmed/33301748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.11.2267
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