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Measurement of protein unfolding/refolding kinetics and structural characterization of hidden intermediates by NMR relaxation dispersion
Detailed understanding of protein function and malfunction hinges on the ability to characterize transiently populated states and the transitions between them. Here, we use (15)N, [Image: see text], and (13)CO NMR R(2) relaxation dispersion to investigate spontaneous unfolding and refolding events o...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107309/ https://ncbi.nlm.nih.gov/pubmed/21562212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105682108 |
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