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Genomic Mechanisms Governing Mineral Homeostasis and the Regulation and Maintenance of Vitamin D Metabolism

Our recent genomic studies identified a complex kidney‐specific enhancer module located within the introns of adjacent Mettl1 (M1) and Mettl21b (M21) genes that mediate basal and PTH induction of Cyp27b1, as well as suppression by FGF23 and 1,25‐dihydroxyvitamin D(3) [1,25(OH)(2)D(3)]. The tissue sp...

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Bibliografske podrobnosti
izdano v:JBMR Plus
Main Authors: Pike, J Wesley, Lee, Seong Min, Benkusky, Nancy A, Meyer, Mark B
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839818/
https://ncbi.nlm.nih.gov/pubmed/33553989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10433
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