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A kidney-specific genetic control module in mice governs endocrine regulation of the cytochrome P450 gene Cyp27b1 essential for vitamin D(3) activation

The vitamin D endocrine system regulates mineral homeostasis through its activities in the intestine, kidney, and bone. Terminal activation of vitamin D(3) to its hormonal form, 1α,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), occurs in the kidney via the cytochrome P450 enzyme CYP27B1. Despite its im...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Biol Chem
मुख्य लेखकों: Meyer, Mark B., Benkusky, Nancy A., Kaufmann, Martin, Lee, Seong Min, Onal, Melda, Jones, Glenville, Pike, J. Wesley
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655528/
https://ncbi.nlm.nih.gov/pubmed/28808057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.806901
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