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A kidney-specific genetic control module in mice governs endocrine regulation of the cytochrome P450 gene Cyp27b1 essential for vitamin D(3) activation
The vitamin D endocrine system regulates mineral homeostasis through its activities in the intestine, kidney, and bone. Terminal activation of vitamin D(3) to its hormonal form, 1α,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), occurs in the kidney via the cytochrome P450 enzyme CYP27B1. Despite its im...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5655528/ https://ncbi.nlm.nih.gov/pubmed/28808057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.806901 |
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