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Genomic Mechanisms Governing Mineral Homeostasis and the Regulation and Maintenance of Vitamin D Metabolism

Our recent genomic studies identified a complex kidney‐specific enhancer module located within the introns of adjacent Mettl1 (M1) and Mettl21b (M21) genes that mediate basal and PTH induction of Cyp27b1, as well as suppression by FGF23 and 1,25‐dihydroxyvitamin D(3) [1,25(OH)(2)D(3)]. The tissue sp...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JBMR Plus
Prif Awduron: Pike, J Wesley, Lee, Seong Min, Benkusky, Nancy A, Meyer, Mark B
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley & Sons, Inc. 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839818/
https://ncbi.nlm.nih.gov/pubmed/33553989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10433
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