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Genomic Mechanisms Governing Mineral Homeostasis and the Regulation and Maintenance of Vitamin D Metabolism

Our recent genomic studies identified a complex kidney‐specific enhancer module located within the introns of adjacent Mettl1 (M1) and Mettl21b (M21) genes that mediate basal and PTH induction of Cyp27b1, as well as suppression by FGF23 and 1,25‐dihydroxyvitamin D(3) [1,25(OH)(2)D(3)]. The tissue sp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:JBMR Plus
Hauptverfasser: Pike, J Wesley, Lee, Seong Min, Benkusky, Nancy A, Meyer, Mark B
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839818/
https://ncbi.nlm.nih.gov/pubmed/33553989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10433
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