Llwytho...
Hypoxia favors chemoresistance in T-ALL through an HIF1α-mediated mTORC1 inhibition loop
Resistance to chemotherapy, a major therapeutic challenge in the treatment of T-cell acute lymphoblastic leukemia (T-ALL), can be driven by interactions between leukemic cells and the microenvironment that promote survival of leukemic cells. The bone marrow, an important leukemia niche, has low oxyg...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Blood Adv |
|---|---|
| Prif Awduron: | , , , , , , , , , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Society of Hematology
2021
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7839374/ https://ncbi.nlm.nih.gov/pubmed/33496749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002832 |
| Tagiau: |
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