Mucosal integrin α4β7 blockade fails to reduce the seeding and size of viral reservoirs in SIV‐infected rhesus macaques

Cellular viral reservoirs are rapidly established in tissues upon HIV‐1/SIV infection, which persist throughout viral infection, even under long‐term antiretroviral therapy (ART). Specific integrins are involved in the homing of cells to gut‐associated lymphoid tissues (GALT) and inflamed tissues, w...

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Bibliographic Details
Published in:FASEB J
Main Authors: Ziani, Widade, Shao, Jiasheng, Fang, Angela, Connolly, Patrick J., Wang, Xiaolei, Veazey, Ronald S., Xu, Huanbin
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2021
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839271/
https://ncbi.nlm.nih.gov/pubmed/33484474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202002235R
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