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Mucosal integrin α4β7 blockade fails to reduce the seeding and size of viral reservoirs in SIV‐infected rhesus macaques

Cellular viral reservoirs are rapidly established in tissues upon HIV‐1/SIV infection, which persist throughout viral infection, even under long‐term antiretroviral therapy (ART). Specific integrins are involved in the homing of cells to gut‐associated lymphoid tissues (GALT) and inflamed tissues, w...

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Bibliografiske detaljer
Udgivet i:FASEB J
Main Authors: Ziani, Widade, Shao, Jiasheng, Fang, Angela, Connolly, Patrick J., Wang, Xiaolei, Veazey, Ronald S., Xu, Huanbin
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839271/
https://ncbi.nlm.nih.gov/pubmed/33484474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202002235R
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