Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity

Immune cells can metabolize glucose, amino acids, and fatty acids (FAs) to generate energy. The roles of different FA species and their impacts on humoral immunity remain poorly understood. Here, we report that proliferating B cells require monounsaturated FAs (MUFAs) to maintain mitochondrial metab...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Zhou, Xian, Zhu, Xingxing, Li, Chaofan, Li, Yanfeng, Ye, Zhenqing, Shapiro, Virginia Smith, Copland, John A., Hitosugi, Taro, Bernlohr, David A., Sun, Jie, Zeng, Hu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839063/
https://ncbi.nlm.nih.gov/pubmed/33406440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108601
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