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Interspecies Scaling of Antibody–Drug Conjugates (ADC) for the Prediction of Human Clearance
Allometric scaling is a useful tool for the extrapolation of pharmacokinetic parameters from animals to humans. The objective of this study was to predict human clearance of antibody–drug conjugates (ADC) allometrically from one to three animal species and compare the predicted human clearance with...
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| Publicado en: | Antibodies (Basel) |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7839014/ https://ncbi.nlm.nih.gov/pubmed/33430196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib10010001 |
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