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Prediction of Clearance of Monoclonal and Polyclonal Antibodies and Non-Antibody Proteins in Children: Application of Allometric Scaling

Allometric scaling can be used for the extrapolation of pharmacokinetic parameters from adults to children. The objective of this study was to predict clearance of therapeutic proteins (monoclonal and polyclonal antibodies and non-antibody proteins) allometrically in preterm neonates to adolescents....

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Bibliografiske detaljer
Udgivet i:Antibodies (Basel)
Hovedforfatter: Mahmood, Iftekhar
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7551666/
https://ncbi.nlm.nih.gov/pubmed/32764408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib9030040
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