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Tyrosine phosphatase SHP2 inhibitors in tumor-targeted therapies
Src homology containing protein tyrosine phosphatase 2 (SHP2) represents a noteworthy target for various diseases, serving as a well-known oncogenic phosphatase in cancers. As a result of the low cell permeability and poor bioavailability, the traditional inhibitors targeting the protein tyrosine ph...
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| Pubblicato in: | Acta Pharm Sin B |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7838030/ https://ncbi.nlm.nih.gov/pubmed/33532178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2020.07.010 |
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