Fibroblast Nox2 (NADPH Oxidase-2) Regulates ANG II (Angiotensin II)–Induced Vascular Remodeling and Hypertension via Paracrine Signaling to Vascular Smooth Muscle Cells

The superoxide-generating Nox2 (NADPH oxidase-2) is expressed in multiple cell types. Previous studies demonstrated distinct roles for cardiomyocyte, endothelial cell, and leukocyte cell Nox2 in ANG II (angiotensin II)–induced cardiovascular remodeling. However, the in vivo role of fibroblast Nox2 r...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Harrison, Craig B., Trevelin, Silvia Cellone, Richards, Daniel A., Santos, Celio X.C., Sawyer, Greta, Markovinovic, Andrea, Zhang, Xiaohong, Zhang, Min, Brewer, Alison C., Yin, Xiaoke, Mayr, Manuel, Shah, Ajay M.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2020
Assuntos:
Basic Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7837692/
https://ncbi.nlm.nih.gov/pubmed/33054395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.315322
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