Fibroblast Nox2 (NADPH Oxidase-2) Regulates ANG II (Angiotensin II)–Induced Vascular Remodeling and Hypertension via Paracrine Signaling to Vascular Smooth Muscle Cells

The superoxide-generating Nox2 (NADPH oxidase-2) is expressed in multiple cell types. Previous studies demonstrated distinct roles for cardiomyocyte, endothelial cell, and leukocyte cell Nox2 in ANG II (angiotensin II)–induced cardiovascular remodeling. However, the in vivo role of fibroblast Nox2 r...

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Bibliografske podrobnosti
izdano v:Arterioscler Thromb Vasc Biol
Main Authors: Harrison, Craig B., Trevelin, Silvia Cellone, Richards, Daniel A., Santos, Celio X.C., Sawyer, Greta, Markovinovic, Andrea, Zhang, Xiaohong, Zhang, Min, Brewer, Alison C., Yin, Xiaoke, Mayr, Manuel, Shah, Ajay M.
Format: Artigo
Jezik:Inglês
Izdano: Lippincott Williams & Wilkins 2020
Teme:
Basic Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7837692/
https://ncbi.nlm.nih.gov/pubmed/33054395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.315322
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