Endoplasmic Reticulum Stress Mediates Vascular Smooth Muscle Cell Calcification via Increased Release of Grp78 (Glucose-Regulated Protein, 78 kDa)-Loaded Extracellular Vesicles

Vascular calcification is common among aging populations and mediated by vascular smooth muscle cells (VSMCs). The endoplasmic reticulum (ER) is involved in protein folding and ER stress has been implicated in bone mineralization. The role of ER stress in VSMC-mediated calcification is less clear. A...

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Detaylı Bibliyografya
Yayımlandı:Arterioscler Thromb Vasc Biol
Asıl Yazarlar: Furmanik, Malgorzata, van Gorp, Rick, Whitehead, Meredith, Ahmad, Sadia, Bordoloi, Jayanta, Kapustin, Alexander, Schurgers, Leon J., Shanahan, Catherine M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Lippincott Williams & Wilkins 2020
Konular:
Translational Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7837691/
https://ncbi.nlm.nih.gov/pubmed/33297752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.315506
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