Secretion of the endoplasmic reticulum stress protein, GRP78, into the BALF is increased in cigarette smokers

BACKGROUND: Identification of biomarkers of cigarette smoke –induced lung damage and early COPD is an area of intense interest. Glucose regulated protein of 78 kD (i.e., GRP78), a multi-functional protein which mediates cell responses to oxidant stress, is increased in the lungs of cigarette smokers...

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Veröffentlicht in:Respir Res
Hauptverfasser: Aksoy, Mark O., Kim, Victor, Cornwell, William D., Rogers, Thomas J., Kosmider, Beata, Bahmed, Karim, Barrero, Carlos, Merali, Salim, Shetty, Neena, Kelsen, Steven G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414124/
https://ncbi.nlm.nih.gov/pubmed/28464871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0561-6
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