Physical Interaction between HPV16E7 and the Actin-Binding Protein Gelsolin Regulates Epithelial-Mesenchymal Transition via HIPPO-YAP Axis

SIMPLE SUMMARY: Human papilloma viruses cause benign or malignant hyper-proliferative lesions in cervical, anogenital and oropharyngeal tissues. Our previous studies revealed that HPV16 E7 alters actin cytoskeleton mainly by binding to and inhibiting Gelsolin. We suggest that the physical interactio...

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Udgivet i:Cancers (Basel)
Main Authors: Matarrese, Paola, Vona, Rosa, Ascione, Barbara, Paggi, Marco G., Mileo, Anna Maria
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7836002/
https://ncbi.nlm.nih.gov/pubmed/33477952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13020353
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