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WWC3 inhibits epithelial–mesenchymal transition of lung cancer by activating Hippo-YAP signaling

BACKGROUND: Though we recently reported that the WWC3 inhibits the invasiveness and metastasis of lung cancer by activating the Hippo pathway, the impact and underlying mechanisms of this process still remain unclear. METHODS: To identify the role of WWC3 in epithelial-mesenchymal transition of lung...

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Détails bibliographiques
Publié dans:Onco Targets Ther
Auteurs principaux: Han, Qiang, Kremerskothen, Joachim, Lin, Xuyong, Zhang, Xiupeng, Rong, Xuezhu, Zhang, Di, Wang, Enhua
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951220/
https://ncbi.nlm.nih.gov/pubmed/29780251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S162387
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