WWC3 inhibits epithelial–mesenchymal transition of lung cancer by activating Hippo-YAP signaling

BACKGROUND: Though we recently reported that the WWC3 inhibits the invasiveness and metastasis of lung cancer by activating the Hippo pathway, the impact and underlying mechanisms of this process still remain unclear. METHODS: To identify the role of WWC3 in epithelial-mesenchymal transition of lung...

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Опубликовано в: :Onco Targets Ther
Главные авторы: Han, Qiang, Kremerskothen, Joachim, Lin, Xuyong, Zhang, Xiupeng, Rong, Xuezhu, Zhang, Di, Wang, Enhua
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2018
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Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951220/
https://ncbi.nlm.nih.gov/pubmed/29780251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S162387
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