Interaction between the human papillomavirus 16 E7 oncoprotein and gelsolin ignites cancer cell motility and invasiveness

The viral oncoprotein E7 from the “high-risk” Human Papillomavirus 16 (HPV16) strain is able, when expressed in human keratinocytes, to physically interact with the actin severing protein gelsolin (GSN). In a previous work it has been suggested that this protein-protein interaction can hinder GSN se...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Matarrese, Paola, Abbruzzese, Claudia, Mileo, Anna Maria, Vona, Rosa, Ascione, Barbara, Visca, Paolo, Rollo, Francesca, Benevolo, Maria, Malorni, Walter, Paggi, Marco G.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239452/
https://ncbi.nlm.nih.gov/pubmed/27072581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8646
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