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Cellular Redox State Acts as Switch to Determine the Direction of NNT-Catalyzed Reaction in Cystic Fibrosis Cells

The redox states of NAD and NADP are linked to each other in the mitochondria thanks to the enzyme nicotinamide nucleotide transhydrogenase (NNT) which, by utilizing the mitochondrial membrane potential (mΔΨ), catalyzes the transfer of redox potential between these two coenzymes, reducing one at the...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Favia, Maria, Atlante, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835933/
https://ncbi.nlm.nih.gov/pubmed/33478087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020967
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