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Kinetic, Structural, and Mutational Analysis of Acyl-CoA Carboxylase From Thermobifida fusca YX

Acyl-CoA carboxylases (AcCCase) are biotin-dependent enzymes that are capable of carboxylating more than one short chain acyl-CoA substrate. We have conducted structural and kinetic analyses of such an AcCCase from Thermobifida fusca YX, which exhibits promiscuity in carboxylating acetyl-CoA, propio...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Shivaiah, Kiran-Kumar, Upton, Bryon, Nikolau, Basil J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835884/
https://ncbi.nlm.nih.gov/pubmed/33511159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.615614
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