Selective allylic hydroxylation of acyclic terpenoids by CYP154E1 from Thermobifida fusca YX

Allylic alcohols are valuable precursors in the synthesis of pharmaceutical intermediates, agrochemicals and natural products. Regioselective oxidation of parental alkenes is a challenging task for chemical catalysts and requires several steps including protection and deprotection. Many cytochrome P...

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Détails bibliographiques
Auteurs principaux: Bogazkaya, Anna M, von Bühler, Clemens J, Kriening, Sebastian, Busch, Alexandrine, Seifert, Alexander, Pleiss, Jürgen, Laschat, Sabine, Urlacher, Vlada B
Format: Artigo
Langue:Inglês
Publié: Beilstein-Institut 2014
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Full Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077532/
https://ncbi.nlm.nih.gov/pubmed/24991288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.137
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