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16S rRNA Gene Copy Number Normalization Does Not Provide More Reliable Conclusions in Metataxonomic Surveys

Sequencing 16S rRNA gene amplicons is the gold standard to uncover the composition of prokaryotic communities. The presence of multiple copies of this gene makes the community abundance data distorted and gene copy normalization (GCN) necessary for correction. Even though GCN of 16S data provided a...

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Detalles Bibliográficos
Publicado en:Microb Ecol
Main Authors: Starke, Robert, Pylro, Victor Satler, Morais, Daniel Kumazawa
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835310/
https://ncbi.nlm.nih.gov/pubmed/32862246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00248-020-01586-7
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