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Correcting for 16S rRNA gene copy numbers in microbiome surveys remains an unsolved problem

The 16S ribosomal RNA gene is the most widely used marker gene in microbial ecology. Counts of 16S sequence variants, often in PCR amplicons, are used to estimate proportions of bacterial and archaeal taxa in microbial communities. Because different organisms contain different 16S gene copy numbers...

詳細記述

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書誌詳細
出版年:Microbiome
主要な著者: Louca, Stilianos, Doebeli, Michael, Parfrey, Laura Wegener
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828423/
https://ncbi.nlm.nih.gov/pubmed/29482646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-018-0420-9
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