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16S rRNA Gene Copy Number Normalization Does Not Provide More Reliable Conclusions in Metataxonomic Surveys

Sequencing 16S rRNA gene amplicons is the gold standard to uncover the composition of prokaryotic communities. The presence of multiple copies of this gene makes the community abundance data distorted and gene copy normalization (GCN) necessary for correction. Even though GCN of 16S data provided a...

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Publicat a:Microb Ecol
Autors principals: Starke, Robert, Pylro, Victor Satler, Morais, Daniel Kumazawa
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835310/
https://ncbi.nlm.nih.gov/pubmed/32862246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00248-020-01586-7
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