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16S rRNA Gene Copy Number Normalization Does Not Provide More Reliable Conclusions in Metataxonomic Surveys

Sequencing 16S rRNA gene amplicons is the gold standard to uncover the composition of prokaryotic communities. The presence of multiple copies of this gene makes the community abundance data distorted and gene copy normalization (GCN) necessary for correction. Even though GCN of 16S data provided a...

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Dettagli Bibliografici
Pubblicato in:Microb Ecol
Autori principali: Starke, Robert, Pylro, Victor Satler, Morais, Daniel Kumazawa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835310/
https://ncbi.nlm.nih.gov/pubmed/32862246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00248-020-01586-7
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