Caveolae-mediated Tie2 signaling contributes to CCM pathogenesis in a brain endothelial cell-specific Pdcd10-deficient mouse model

Cerebral cavernous malformations (CCMs) are vascular abnormalities that primarily occur in adulthood and cause cerebral hemorrhage, stroke, and seizures. CCMs are thought to be initiated by endothelial cell (EC) loss of any one of the three Ccm genes: CCM1 (KRIT1), CCM2 (OSM), or CCM3 (PDCD10). Here...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhou, Huanjiao Jenny, Qin, Lingfeng, Jiang, Quan, Murray, Katie N., Zhang, Haifeng, Li, Busu, Lin, Qun, Graham, Morven, Liu, Xinran, Grutzendler, Jaime, Min, Wang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835246/
https://ncbi.nlm.nih.gov/pubmed/33495460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20774-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados