Impact of phosphodiesterases PDE3 and PDE4 on 5-hydroxytryptamine receptor4-mediated increase of cAMP in human atrial fibrillation

Atrial fibrillation (AF)–associated remodeling includes contractile dysfunction whose reasons are only partially resolved. Serotonin (5-HT) increases contractile force and causes arrhythmias in atrial trabeculae from patients in sinus rhythm (SR). In persistent atrial fibrillation (peAF), the force...

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Foilsithe in:Naunyn Schmiedebergs Arch Pharmacol
Main Authors: Dolce, Bernardo, Christ, Torsten, Grammatika Pavlidou, Nefeli, Yildirim, Yalin, Reichenspurner, Hermann, Eschenhagen, Thomas, Nikolaev, Viacheslav O., Kaumann, Alberto J, Molina, Cristina E
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer Berlin Heidelberg 2020
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835186/
https://ncbi.nlm.nih.gov/pubmed/32949251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-020-01968-1
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