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AML-337: Targeting E-Selectin with GMI-1271 Overcomes Microenvironment-Mediated Resistance to Venetoclax/HMA Therapy

Acute myeloid leukemia (AML) is an aggressive heterogeneous hematologic disease with high mortality in patients older than 60 years. Clinical studies have proven that combinations of FDA-approved Bcl-2 inhibitor, venetoclax and hypomethylating agents (HMA) are highly effective in elderly patients wi...

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Dettagli Bibliografici
Pubblicato in:Clin Lymphoma Myeloma Leuk
Autori principali: Chang, Kyung Hee, Zhang, Weiguo, Basyal, Mahesh, Ostermann, Lauren, Fogler, William, Magnani, John, Andreeff, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7833936/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2152-2650(20)30760-6
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