Yüklüyor......
CDK1/2/5 blockade: killing two birds with one stone
Pancreatic ductal adenocarcinoma (PDAC) is an immune resistant tumor. We recently demonstrated that inhibiting CDK1/2/5 by dinaciclib not only blocks immune checkpoint expression, but also triggers histone-dependent immunogenic cell death. This dual mechanism turns immunologically “cold” tumor micro...
Kaydedildi:
| Yayımlandı: | Oncoimmunology |
|---|---|
| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Taylor & Francis
2021
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7833763/ https://ncbi.nlm.nih.gov/pubmed/33537177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2021.1875612 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|