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Inhibition of the mevalonate pathway to override chemoresistance and promote the immunogenic demise of cancer cells: Killing two birds with one stone

The mevalonate pathway is an attractive target for cancer therapy not only to override multidrug resistance but also to promote the immunogenic demise of malignant cells. Recent data indicate that aminobisphosphonates are superior to statins for the pharmacological manipulation of the mevalonate pat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Riganti, Chiara, Massaia, Massimo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3850498/
https://ncbi.nlm.nih.gov/pubmed/24327936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.25770
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