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The NFκB Antagonist CDGSH Iron-Sulfur Domain 2 Is a Promising Target for the Treatment of Neurodegenerative Diseases

Proinflammatory response and mitochondrial dysfunction are related to the pathogenesis of neurodegenerative diseases (NDs). Nuclear factor κB (NFκB) activation has been shown to exaggerate proinflammation and mitochondrial dysfunction, which underlies NDs. CDGSH iron-sulfur domain 2 (CISD2) has been...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kung, Woon-Man, Lin, Muh-Shi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7832822/
https://ncbi.nlm.nih.gov/pubmed/33477809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020934
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